"After three months of use of essence containing ergot thiophene, skin elasticity increased by 23% and wrinkle depth decreased by 18%." At the 2025 Pujiang Innovation Forum InnoMatch Technology Transfer Conference, the test data shared by an experiencer attracted attention. On that day, Ushi Beauty Health Dream Factory announced the realization of high-purity ergot sulfide through domestic production, breaking the 15 year technological monopoly of overseas brands.
As a natural antioxidant, ergothionein can effectively eliminate free radicals and delay cell aging, but traditional extraction processes are complex and costly. The integrated technology of "microbial fermentation membrane separation" jointly developed by Ushi and Jiangnan University has increased the purity of ergothionein to 99.2% and reduced production costs by 60%. "The technology has applied for 18 invention patents, and the mass production scale can reach 5 tons per year, which can meet the demand of 80% of the country's high-end anti-aging products." The person in charge of the enterprise introduced that its first anti-aging face cream containing this ingredient has been launched, the price is only 1/3 of that of imported similar products, and the sales volume in the first month of launch has exceeded 100000 bottles.
The clinical test conducted by the Institute of Dermatology of the Chinese Academy of Sciences shows that this domestic ergot thiophene product has the same performance as international first-line brands in improving skin barrier function, reducing photoaging damage and other indicators, and some data are even better than the latter.
Optoelectronic equipment innovation: "Ice Beauty MJ6" landing, non-invasive anti-aging efficiency increased by 50%
In addition to breakthroughs in active ingredients, significant progress has also been made in domestic optoelectronic anti-aging equipment. The "Ice Beauty MJ6" overclocking ice guided device developed by Meijingling Medical, in collaboration with Peking University Third Hospital and Tsinghua University, made its global debut at the conference. The device adopts a dual-mode of "overclocking RF+low-temperature protection", which can penetrate to the dermis layer to stimulate collagen regeneration, while controlling the epidermal temperature at 38 ℃, solving the pain points of traditional phototherapy that are prone to redness and swelling and have a long recovery period.
The traditional Thermage treatment requires a 7-day recovery period, and this device can provide normal skincare after treatment, with a pain score reduced from 4.5 points to 1.2 points. "The director of the Dermatology Department at Peking University Third Hospital, who participated in the research and development, introduced that in a clinical trial, after 3 treatments, the improvement rate of facial wrinkles in 120 subjects reached 82%, the skin firmness increased by 40%, and the efficiency was 50% higher than that of traditional devices.
At present, the "Ice Beauty MJ6" has obtained Class III medical device certification from the National Medical Products Administration. The first batch of 50 devices have been deployed in 20 tertiary hospitals, including Peking Union Medical College Hospital and Shanghai Ruijin Hospital. The appointment schedule for private medical beauty institutions has been delayed for three months.
Industrial fund support: 50 million capital injection to incubate anti-aging innovation achievements
To accelerate technological transformation, Ushi Beauty and Health Dream Factory simultaneously announced the establishment of a 50 million yuan "Ushi Koyanmei Science Partner Founding Fund", focusing on investing in early innovation projects in the anti-aging field. The fund will focus on three major directions: stem cell anti-aging, epigenetic regulation, and intelligent skincare devices, providing full chain support from laboratory to market for research teams. The fund manager stated that they have reached investment intentions with eight research teams including the Chinese Academy of Sciences and Fudan University, involving cutting-edge technologies such as skin stem cell storage and anti-aging gene testing.
This measure is not an isolated case. According to industry data, in the first half of 2025, the financing amount in the domestic anti-aging field reached 3.2 billion yuan, a year-on-year increase of 85%, of which industry university research cooperation projects accounted for over 60%. The "Anti Aging Translational Medicine Center" jointly established by Shanghai Jiao Tong University School of Medicine and a pharmaceutical company has recently successfully transformed the "telomerase activating peptide" technology into oral anti-aging products and entered the clinical trial stage.
The size of China's anti-aging market has exceeded 200 billion yuan, but the high-end market has long been dominated by overseas brands, "said Sang Jingmin, Secretary General of the China Beauty Expo. With breakthroughs in domestic technology, capital support, and improved standards, the market share of domestic anti-aging products is expected to increase from the current 35% to 60% in the next 3-5 years, achieving a leap from" following "to" leading ".